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KratomCaps.com | Kratom Alkaloids

Kratom Alkaloids
Kratom contains over 25 alkaloids, see what they are and why they make kratom so effective in so many areas


Mitragynine
Analgesic (pain killer), antitussive (capable of relieving or suppressing coughing), antidiarrheal (prevents diarrhea), adrenergic (activated by or capable of releasing epinephrine or an epinephrine like substance, especially in the sympathetic nervous system), antimalarial (preventing or relieving the symptoms of malaria). Believed to be one of the top two active alkaloids in kratom with 7-hydroxymitragynine being the other.

Other resources:
Kratom Bullet Wikipedia: Mitragynine

Kratom Bullet Mitragynine Depression Study


7-hydroxymitragynine
Analgesic (also known as a painkiller), antitussive (capable of relieving or suppressing coughing), antidiarrheal (used to prevent or treat diarrhea). Studies suggest that the opioid effect of kratom is mainly based on the activity of 7-hydroxymitragynine.

Other resources:
Kratom Bullet Wikipedia: 7-hydroxymitragynine

Kratom Bullet Clinical Test at Chiba University: Japan
Kratom Bullet Pharmacological Studies


Ajmalicine (Raubasine)
Cerebrocirculant (movement of blood through the network of blood vessels supplying the brain), antiaggregant (decrease platelet aggregation and inhibit blood clot formation), anti-adrenergic (at alpha-1), sedative, anticonvulsant, smooth muscle relaxer

Other resources:
Kratom Bullet Wikipedia: Ajmalicine


Corynantheidine (Rauhimbine)
Opioid antagonist (a receptor antagonist that acts on opioid receptors).

Other resources:
Kratom Bullet Wikipedia: Corynantheidine


Corynoxeine
Calcium channel blocker.


Corynoxine A and B
Dopamine mediators


(-) Epicatechin
Antioxidant, antiaggregant (decrease platelet aggregation and inhibit blood clot formation), antibacterial, antidiabetic, antihepatitic, anti-inflammatory, anti-leukemic, antimutagenic, antiperoxidant, antiviral, cancer preventative, alpha-amylase inhibitor

Other resources:
Kratom Bullet Wikipedia: Epicatechin

Kratom Bullet Phytochemicals: Epicatechin


List of known Alkaloids in Kratom:

Ajmalicine (Raubasine) Cerebrocirculant, antiaggregant, anti-adrenergic (at alpha-1), sedative, anticonvulsant, smooth muscle relaxer
Corynantheidine Opioid antagonist
Corynoxeine Calcium channel blocker
Corynoxine A and B Dopamine mediating anti-locomotives
(-)-Epicatechin Antioxidant, antiaggregant, antibacterial, antidiabetic, antihepatitic, anti-inflammatory, anti-leukemic, antimutagenic, antiperoxidant, antiviral, cancer preventative, alpha-amylase inhibitor
9-Hydroxycorynantheidine Partial opioid agonist
7-Hydroxymitragynine Analgesic, antitussive, antidiarrheal; primary psychoactive in kratom
Isomitraphylline Immunostimulant, anti-leukemic
Isopteropodine Immunostimulant
Mitragynine Analgesic, antitussive, antidiarrheal, adrenergic, antimalarial, possible psychedelic (5-HT2A) antagonist
Mitraphylline Vasodilator, antihypertensive, muscle relaxer, diuretic, anti-amnesic, possible immunostimulant
Paynantheine Smooth muscle relaxer
Rhynchophylline Vasodilator, antihypertensive, calcium channel blocker, antiaggregant, anti-inflammatory, antipyretic, anti-arrhythmic, antithelmintic
Speciociliatine Weak opioid agonist
Speciogynine Smooth muscle relaxer
Speciophylline Anti-leukemic
Tetrahydroalstonine Hypoglycemic, anti-adrenergic (at alpha-2)

 

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